Histopathology and ultrastructure of the liver under combined action of narcotics and hepatitis C and B viruses.

Autor: Nepomnyashchikh, G., Tolokonskaya, N., Sakharova, E., Aidagulova, S., Mezentseva, G., Nepomnyashchikh, L.
Zdroj: Bulletin of Experimental Biology & Medicine; Sep1999, Vol. 128 Issue 3, p963-966, 4p
Abstrakt: Liver autopsy material from opioid addicts with viral hepatitis C and C+B showed hepatocyte dystrophy associated with lipid infiltration, hyperplasia of lymphoid tissue, and perivascular fibrosis. Alteration of hepatocytes were most pronounced in patients with hepatitis C+B. Ultrastructure of hepatocytes is characterized by a reduction of protein synthesizing compartment, an increase in volume density of smooth cytoplasmic reticulum, appearance of megamitochondria, and pronounced collagenization of the Disse space. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index