Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles containing benzothiazolylthiol grouping.

Autor: Kelarev, V., Silin, M., Grigor'eva, N., Koshelev, V.
Zdroj: Chemistry of Heterocyclic Compounds; Feb2000, Vol. 36 Issue 2, p207-213, 7p
Abstrakt: A series of 2,5-substituted 1,3,4-oxadiazoles containing 2-benzothiazolylthiomethyl grouping has been synthesized by condensing derivatives of (2-benzothiazolylthio)acetic acid with imino ester hydrochlorides and hydrazides of carboxylic acids, by the cyclodehydration of N-acyl-N′-(2-benzothiazolylthioacetyl)hydrazines under the action of POCl, and also by the reaction of 2-mercaptobenzothiazole with 2-chloromethyl-1,3,4-oxadiazoles in the presence of sodium methylate. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index