| Autor: |
Semioshkin, A., Artemov, V., Ivanov, V., Ptashits, G., Petrovskii, P., Shestopalov, A., Bregadze, V., Litvinov, V. |
| Zdroj: |
Chemistry of Heterocyclic Compounds; Jun1998, Vol. 34 Issue 6, p688-691, 4p |
| Abstrakt: |
Substituted 2-( o-carboran-1-yl)methylthio-3-cyanopyridines and-pyrimidines undergo Thorpe-Ziegler cyclization under the influence of KOH in DMF to give the corresponding thienopyridines and thienopyrimidines. The reaction is complicated by a side reaction in which the closo-carborane nucleus is converted to a nido-system. The yield of thienopyridines containing a closo-carborane unit is increased by introduction of an acceptor substituent in the pyridine ring. Destruction of the closo-carborane nucleus is not observed with the pyrimidine derivatives. The structures of the series of new carborane-containing thienopyridines and pyrimidines was confirmed by spectroscopic methods. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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