| Autor: |
Parshikov, I., Terent'ev, P., Piskunkova, N., Gracheva, R., Bulakhov, G. |
| Zdroj: |
Chemistry of Heterocyclic Compounds; May1997, Vol. 33 Issue 5, p523-526, 4p |
| Abstrakt: |
In the microbiological transformation of 4-phenylpyrrolidine by growing strains of the fungi Cunninghamella, Beauveria, and Penicillium, its 1-ethyl and 1-acetyl derivatives are formed; these are subsequently oxidized at positions 2 and 3. In contrast, 1-benzoyl-4-phenylpyrrolidine is hydroxylated by those same cultures in positions 3 and 5. For the corresponding 2-pyrrolidone derivatives, the 4-phenyl-2-pyrrolidone is not transformed by these fungi, while the 1-benzoyl-2-pyrrolidone is hydrolyzed at the benzamide group under the same conditions. The structures of the products from these transformations were determined by mass spectrometry. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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