Synthesis and neurotropic properties of N-acylphenothiazines.

Autor: Lukevics, E., Trushule, M., Germane, I., Turovskii, I.
Zdroj: Chemistry of Heterocyclic Compounds; Feb1997, Vol. 33 Issue 2, p229-233, 5p
Abstrakt: N-Acylphenothiazines (derivatives of furan and phthalylamino acids) were synthesized, and their neurotropic properties were studied. It was established that the derivatives of phthalyl-ψ-aminobutyric acid increase the duration of hexenal narcosis (by 1.7 times) and increase the stimulant activity of phenamine (by 2.1 times). The glycine derivative prolongs the life of animals under the conditions of hypoxia by 77%. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index