Autor: |
Sicinski, Piotr, Weinberg, Robert |
Zdroj: |
Journal of Mammary Gland Biology & Neoplasia; Oct1997, Vol. 2 Issue 4, p335-342, 8p |
Abstrakt: |
Cyclin D1 is a critical component of the core cell cycle machinery. Mice lacking cyclin D1 develop mammary glands that fail to undergo normal lobuloalveolar proliferation during pregnancy. Thus, cyclin D1 seems to play a critical role in pregnancy-induced proliferation of mammary epithelium. Cyclin D1 also participates in neoplasia, as the majority of human mammary carcinomas contain elevated levels of this cyclin. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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