| Autor: |
Danilova, R., Rud'ko, O., Korotkova, T., Obukhova, M., Ashmarin, I. |
| Zdroj: |
Neuroscience & Behavioral Physiology; Mar2002, Vol. 32 Issue 2, p189-194, 6p |
| Abstrakt: |
Active immunization of white rats with cholecystokinin-4 covalently linked to the antigen carrier BSA evoked long-lasting changes in the rats' behavior, which were in the opposite direction to the anxiogenic effects of cholecystokinin-4 itself, showing that immunization had anxiolytic effects. Immunoenzyme analysis demonstrated the presence of antibodies to cholecystokinin-4 in the serum of immunized rats. These data are interesting from the point of view of correcting pathological anxiety and fear states by inverse immunoregulation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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