| Autor: |
Vaskova, E. A., Pavlova, S. V., Shevchenko, A. I., Zakian, S. M. |
| Předmět: |
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| Zdroj: |
Russian Journal of Genetics; Apr2010, Vol. 46 Issue 4, p385-393, 9p, 2 Diagrams, 1 Chart |
| Abstrakt: |
During meiosis, heteromorphic mammalian X and Y chromosomes in males undergo transcription silencing and form a compact structure, the XY body, containing specific modifications of the chromatin. In this review, we consider the dynamics of sex chromosome inactivation and discuss the suggestion that the paternally inherited X-chromosome preserves inactivated state in zygote. This state results from meiotic silencing and is prone to imprinted inactivation, which is observed in mammalian females at early embryogenetic stages. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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