Development and validation of computational models of cellular interaction.

Autor: Smallwood, R., Holcombe, W., Walker, D.
Zdroj: Journal of Molecular Histology; Sep2004, Vol. 35 Issue 7, p659-665, 7p
Abstrakt: In this paper we take the view that computational models of biological systems should satisfy two conditions – they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be available. A modelling paradigm for developing a predictive computational model of cellular interaction is described, and methods of providing robust validation against biological models are explored, followed by a consideration of software issues. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index