Developmental plasticity of CNS microglia.

Autor: Santambrogio, L., Belyanskaya, S.L., Fischer, F.R., Cipriani, B., Brosnan, C.F., Ricciardi-Castagnoli, P., Stern, L.J., Strominger, J.L., Riese, R.
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 05/22/2001, Vol. 98 Issue 11, p6295, 6p, 11 Color Photographs, 6 Diagrams, 8 Graphs
Abstrakt: Reports that parenchymal microglia are uncommitted myeloid progenitors of immature dendritic cells and macrophages by several criteria, including surface expression of 'empty' class II MHC protein and their cysteine protease (cathepsin) profile. Role of microglia in central nervous system inflammatory conditions; Differentiation of microglia along the myeloid lineage.
Databáze: Complementary Index