1H, 13C and 15N resonance assignment of 6aJL2(R25G), a highly fibrillogenic λVI light chain variable domain.

Autor: Gutiérrez-González, Luis, Muresanu, Lucia, Pozo-Yauner, Luis, Sánchez, Rosalba, Guereca, Leopoldo, Becerril, Baltazar, Lücke, Christian
Zdroj: Biomolecular NMR Assignments; Dec2007, Vol. 1 Issue 2, p159-161, 3p
Abstrakt: An allotypic variation at position 25 influences the fibrillogenicity of λVI light chains, which are related to humoral immune response and have been associated with AL amyloidosis. The full resonance assignment and a preliminary structural characterization of 6aJL2(R25G) are reported. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index