| Autor: |
Lynch, Henry, Brand, Randall, Deters, Carolyn, Fusaro, Ramon |
| Zdroj: |
Current Gastroenterology Reports; Mar2001, Vol. 3 Issue 2, p121-128, 8p |
| Abstrakt: |
Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A ( p16) germline mutation that expresses both pancreatic cancer and malignant melaonoma may constitute a new hereditary pancreatic cancer-prone syndrome. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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