Aortic valve replacement and coronary bypass in a patient with homozygous familial hypercholesterolemia.

Autor: Dixit, Mahadev, Gan, Mohan, Pradeep, Kizakke, Nishanimath, Narendra, Vagarali, Anand, Dayal, Aruneshwari
Zdroj: Indian Journal of Thoracic & Cardiovascular Surgery; Mar2007, Vol. 23 Issue 1, p36-38, 3p
Abstrakt: Homozygous familial hypercholesterolemia is a rare defect of lipid metabolism characterized by markedly elevated levels of serum total cholesterol. The patients develop premature atherosclerosis and aortic stenosis. Surgical management is complicated by the dense calcification of the ascending aorta and the small aortic root. We present our experience with the management of such a patient with coronary artery disease and aortic valvular and supra-valvular stenosis. She underwent coronary bypass and aortic valve replacement with a root enlargement. The calcified and atheromatous ascending aorta resulted in her developing a stroke. The few reported cases are reviewed to suggest techniques to prevent this lethal complication. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index