Experience with autologous pericardial patch closure of ventricular septal defect.

Autor: Okwulehie, Vincent, Dharmapuram, Anil, Swain, Sunil, Ramdoss, Nagarajan, Sundararaghavan, Sreekanthan, Kona, Samba
Zdroj: Indian Journal of Thoracic & Cardiovascular Surgery; Oct2006, Vol. 22 Issue 4, p212-214, 3p
Abstrakt: Conventionally, Ventricular Septal Defects (VSDs) are repaired with synthetic patch—Dacron (polyethylene terephthalate) or Goretex (expanded polytetrafluoroethylene). Recently, we began using glutaraldehyde—treated autologous pericardial patch to repair VSDs. We review our experience. Between July to November 2005, 60 children had their VSDs repaired with glutaraldehyde—treated autologous pericardium. There were 40 males and 20 females, aged between 5 months and 12 years with a median age of 1 year. The diagnosis was isolated VSD in 37 patients, multiple VSD in 3; Tetralogy of Fallot (TOF) in 15 and Double Outlet Right Ventricle (DORV) in 5 patients. The chest was opened by a median sternotomy incision. After establishing cardiopulmonary bypass, a strip of pericardium was harvested from the patient and fixed in 0.6% glutaraldehyde (Polyscientific, Bayshore, NY) for about 20 minutes. It was then washed out with 0.9% saline solution. The defect was repaired with 4/0 or 5/0 prolene suture using a continuous suture technique. There was no hospital mortality. Postoperative echocardiogram revealed trivial shunts in 10 patients. Follow up was for 3 to 6 months (mean 2 months). No patient required reoperation for residual VSD. Glutaraldehyde—treated autologous pericardium is an excellent material for surgical patch clousre of VSD. It is easily available and does not require sterilization. Further follow-up is required to assess its long term efficacy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index