Serum immunoglobulins, IgG subclasses, isohemagglutinins and complement-3 levels in patients with thalassemia major.

Autor: Vergin, Canan, Kutukculer, Necil, Cetingul, Nazan, Nisli, Gungor, Caglayan, Suat, Oztop, Senay, Vergin, C, Kutukculer, N, Cetingul, N, Nisli, G, Caglayan, S, Oztop, S
Zdroj: Indian Journal of Pediatrics; Mar1997, Vol. 64 Issue 2, p215-219, 5p
Abstrakt: Serum IgG, IgM, IgA, IgG subclasses (IgG1, G2, G3, G4), isohemagglutinins and complement-3 concentrations were measured in 23 beta-thalassemic patients suffering from recurrent infections. No significant abnormalities were found in these humoral immunity investigations, both in splenectomized and non-splenectomized patients. On the other hand, iron overload or repeated blood transfusions were not found to down-regulate the humoral immune system of thalassemic patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index