Increased accumulations of AMsopropyl- p-[123I]-iodoamphetamine related to tumefactive multiple sclerosis.

Autor: Sagiuchi, Takao, Oka, Hidehiro, Utsuki, Satoshi, Sato, Kimitoshi, Kobayasm, Ikuo, Asano, Yuuji, Ishii, Katsumi, Fujii, Kiyotaka
Zdroj: Annals of Nuclear Medicine; Oct2005, Vol. 19 Issue 7, p603-606, 4p
Abstrakt: We present a 21-year-old woman with tumefactive multiple sclerosis (MS) that exhibited a rapidly progressive course. There were multiple tumor-mimicking contrast-enhance lesions with surrounding edema and mass effect on magnetic resonance imaging. Both early and delayed brain single photon emission computed tomography (SPECT) with N-isopropyl- p-[123I]-iodoamphetamine demonstrated increased accumulations of the tracer and a high retention on the lesions. The SPECT findings represent a diagnostic pitfall for distinguishing MS from malignant brain tumors in patients with intracranial tumor-like lesions. [ABSTRACT FROM AUTHOR]
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