Technetium-99m-tetrofosmin imaging of lung cancer: relationship with histopathology.

Autor: Takekawa, Hironori, Shinano, Hideki, Tsukamoto, Eriko, Koseki, Yukio, Ikeno, Toshiyuki, Miller, Fredrick, Kawakami, Yoshikazu, Takekawa, H, Shinano, H, Tsukamoto, E, Koseki, Y, Ikeno, T, Miller, F, Kawakami, Y
Zdroj: Annals of Nuclear Medicine; Apr1999, Vol. 13 Issue 2, p71-75, 5p
Abstrakt: Tc-99m-tetrofosmin is an agent to delineate cancer. To elucidate the usefulness of Tc-99m-tetrofosmin scintigraphy, we analyzed the relationship between the uptake of Tc-99m-tetrofosmin and histopathology in patients with lung cancer. SPECT studies were conducted twice: 15 minutes (early scan), and 60 minutes (delayed scan), after intravenous injection of 740 MBq Tc-99m-tetrofosmin. We calculated the retention index in order to evaluate the degree of Tc-99m-tetrofosmin retention in the primary tumor. The retention indices were significantly lower in squamous cell carcinoma than those of small cell carcinoma or adenocarcinoma. As the retention indices of Tc-99m-tetrofosmin were different in each histopathology, the index might play a part as a tumor marker of lung cancer. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index