The prognostic impact of successful cardioversion of atrial fibrillation in patients with organic heart disease.

Autor: Kleemann, Thomas, Becker, Torsten, Dönges, Klaus, Vater, Margit, Gut, Bern, Schneider, Steffen, Senges, Jochen, Seidl, Karlheinz
Zdroj: Clinical Research in Cardiology; Feb2007, Vol. 96 Issue 2, p103-108, 6p
Abstrakt: The aim of the study was to evaluate the prognostic impact of successful cardioversion (CV) compared to failed CV in patients with atrial fibrillation (AF) and organic heart disease. A total of 471 consecutive patients with organic heart disease from the prospective single center anticoagulation registry ANTIK who underwent CV of AF or atrial flutter were analyzed. 417 patients (89%) could be successfully cardioverted. In 54 patients (11%) CV failed, these patients remained in AF. After 5 years there were 92 (24%) deaths among patients with restored sinus rhythm at index admission and 20 (38%) deaths among those who remained in AF after CV (unadjusted OR 1.9, 95% CI 1.1–3.6). After adjustment for age, gender and ejection fraction, successful CV was not associated with a beneficial effect on mortality (OR 0.72, 95% CI 0.43–1.21). Thus, successful CV is not an independent predictor of mortality on multivariate analysis. However, it remains a marker for a better prognosis in patients with organic heart disease as these patients have a lower unadjusted longterm mortality. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index