Midtrimester termination of complicated pregnancy with oral misoprostol.

Autor: Batioğlu, S., Tonguç, E., Haberal, A., Çelikkanat, H., Bağis, T.
Zdroj: Advances in Contraception; Mar1997, Vol. 13 Issue 1, p55-61, 7p
Abstrakt: To define the mean effective dose of oral misoprostol, a PGE2 methylanalogue, for terminating midtrimester complicated pregnancy without producing significant side-effects and complications, forty-two patients with intrauterine complicated pregnancies of 14-28 weeks were treated with oral misoprostol. All patients were observed after the initial dose (200 µg). If there was no contraction of the uterus or no vaginal bleeding, a supplementary dose of 200 µg misoprostol was given once each hour, with an average total dose of 1000 µg being given (min. 200 µg, max. 1200 µg). Abortion was successfully induced in 39 women (92.9%); there were 3 failures (7.1%). The mean time from initial dose to abortion was 9 h. No important side-effects or complications were noted. This study demonstrated that the use of oral misoprostol is a simple, inexpensive and easy procedure for termination of second trimester complicated pregnancy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index