| Autor: |
Kibria, S.M.G., Homer-Vanniasinkam, S., Gough, M.J., Mavor, A.I.D. |
| Předmět: |
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| Zdroj: |
British Journal of Surgery; May2001 Supplement 1, Vol. 88, p77, 2p |
| Abstrakt: |
Aims: Early postoperative pain limits mobilization after varicose vein surgery, which is increasingly performed as a day-case procedure. This study investigated the safety of a new method of administering local anaesthesia and the effect of this technique on postoperative pain. Methods: The study group comprised 20 consecutive patients undergoing unilateral long saphenous vein stripping for varicose veins. Bupivacaine 0.5 per cent, 10 mL, was introduced into the tract left after stripping the long saphenous vein by pulling a bupivacaine-soaked gauze into the tract for the remainder of the operation. Blood samples were taken before placing the gauze, and at 0.5, 1, 2, 4, 6 and 8 h afterwards, and serum bupivacaine levels were assessed by gas liquid chromatography. Postoperatively the pain levels were assessed by a numerical rating scale and by the analgesic requirements during that period. Results: None of the patients showed any symptoms or signs of bupivacaine toxicity. Peak serum levels occurred 1 h after introduction of bupivacaine (cumulative analysis). The maximum, recorded serum level (122.7 ng) was 200 times less than the known toxic level. 18/20 patients considered pain relief excellent and none of the 18 required any postoperative analgesia during the first 24 h. A historical control group of 20 patients needed between two and five (median three doses) doses of analgesia during the same postoperative period. Conclusions: This method of delivering bupivacaine to the long saphenous vein tract after stripping is safe and provides excellent postoperative analgesia. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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