| Autor: |
Young Rim Song, Sun Jin You, Yun-Mi Lee, Ho Joon Chin, Dong-Wan Chae, Yun Kyu Oh, Kwon Wook Joo, Jin Suk Han, Ki Young Na |
| Předmět: |
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| Zdroj: |
Nephrology Dialysis Transplantation; Jan2010, Vol. 25 Issue 1, p77-85, 9p, 1 Chart, 7 Graphs |
| Abstrakt: |
Background. Chronic hypoxia in the kidney has been suggested as a final common pathway to end-stage renal disease. Hypoxia-inducible factor (HIF) is a transcription factor that regulates cellular hypoxic responses, and it is a promising target with therapeutic potential in various kidney disease models. In this study, we investigated whether HIF activation could attenuate renal injury in the rat remnant kidney model. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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