| Autor: |
Dreger, Henryk, Westphal, Kera, Wilck, Nicola, Baumann, Gert, Stangl, Verena, Stangl, Karl, Meiners, Silke |
| Předmět: |
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| Zdroj: |
Cardiovascular Research; Jan2010, Vol. 85 Issue 2, p395-403, 9p, 5 Graphs |
| Abstrakt: |
Aims: Increased levels of reactive oxygen species cause oxidative stress and severely damage lipids, proteins, and DNA. We have previously shown that partial proteasome inhibition induces an antioxidative gene pattern in endothelial cells. Here, we elucidate the mechanisms of proteasome inhibitor-mediated upregulation of antioxidative enzymes and cytoprotection. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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