Electroretinogram and cue-elicited craving in withdrawn cocaine-dependent patients: a replication.

Autor:	Smelson, David A., Roy, Alec, Roy, Monique, Tershakovec, Dora, Engelhart, Charles, Losonczy, Miklos F., Smelson, D A, Roy, A, Roy, M, Tershakovec, D, Engelhart, C, Losonczy, M F
Předmět:	ELECTRORETINOGRAPHY DRUG withdrawal symptoms COCAINE abuse DRUG addiction COCAINE ELECTRODIAGNOSIS
Zdroj:	American Journal of Drug & Alcohol Abuse; May2001, Vol. 27 Issue 2, p391-397, 7p
Abstrakt:	Background: We previously reported that cocaine-dependent patients with a reduced blue cone b wave electroretinogram (ERG) responses had significantly more cue-elicited craving.Methods: A new series of 21 recently withdrawn cocaine-dependent patients completed a craving questionnaire at baseline and following cue exposure; an ERG was also performed.Results: Cocaine-dependent patients with a blunted ERG blue cone response (<0.5 microV) showed greater increases in craving following cue exposure. When subjects were included from our preliminary study (N = 14), these differences became highly significant.Conclusions: Patients with a reduced ERG response may represent a subgroup more vulnerable to cocaine craving and future relapse. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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