Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex...

Autor: Xiaosheng Wu, Kasper, Lawyrn H., Mantcheva, Ralitsa T., Mantchev, George T., Springett, Margaret J., van Deursen, Jan M.A.
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 03/13/2001, Vol. 98 Issue 6, p3191, 6p, 56 Diagrams, 1 Chart, 1 Graph
Abstrakt: Reports that the disruption of murine NUP98 gene that encode precursor proteins causes selective changes in nuclear pore complex stoichiometry and function. Importance of NUP98 in mouse gastrulation, a developmental stage associated with rapid cell proliferation; Lack of role in basal cell growth.
Databáze: Complementary Index