| Autor: |
Kara, Firas M., Doty, Stephen B., Boskey, Adele, Goldring, Steven, Zaidi, Mone, Fredholm, Bertil B., Cronstein, Bruce N. |
| Předmět: |
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| Zdroj: |
Arthritis & Rheumatism; Feb2010, Vol. 62 Issue 2, p534-541, 8p, 5 Graphs |
| Abstrakt: |
The article presents a study on the effects of Adenosine A1 receptors in regulating bone resorption in mice. The study analyzes the adenosine A1 receptor-knockout mice bone mineral density (BMD) and their bone volume was determined using microfocal computed tomography (micro-CT). It suggests that adenosine A1 receptor is significant in bone turnover regulation and makes an efficient treatment target for prosthetic joint loosening and osteoporosis. |
| Databáze: |
Complementary Index |
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