Clinical outcomes of self-expandable metal stent and prognostic factors for stent patency in gastric outlet obstruction caused by gastric cancer.

Autor: Yu Kyung Cho, Sang Woo Kim, Won Haeng Hur, Kwan Woo Nam, Jae Hyuck Chang, Jae Myung Park, In Seok Lee, Myung-Gyu Choi, In-Sik Chung, Cho, Yu Kyung, Kim, Sang Woo, Hur, Won Haeng, Nam, Kwan Woo, Chang, Jae Hyuck, Park, Jae Myung, Lee, In Seok, Choi, Myung-Gyu, Chung, In-Sik
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Zdroj: Digestive Diseases & Sciences; Mar2010, Vol. 55 Issue 3, p668-674, 7p, 6 Charts, 2 Graphs
Abstrakt: The aim of this study was to assess clinical outcomes of endoscopic stenting for a gastric outlet obstruction caused by gastric cancer and the prognostic factors for stent patency by reviewing medical records. Eighty-one stents were inserted into 75 patients (48 men, average age 66 years). The technical and clinical success rates were 98 and 87%, respectively. The median stent patency was 55 days (95% CI 40-70 days). The median survival was 79 days (95% CI 58-123 days). Stent reobstruction caused by tumor ingrowth or overgrowth occurred in 25 cases (31%). Cox multivariate regression analysis showed that covered stents (odds ratio 0.29, 95% CI 0.11-0.76; P = 0.01) and chemotherapy after stent placement (odds ratio 0.34, 95% CI 0.13-0.91; P = 0.03) were significant prognostic factors for stent patency. This study found that endoscopic stenting is a safe and effective palliation treatment for malignant gastric outlet obstruction and a covered stent and chemotherapy are significant prognostic factors for stent patency. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index