Reduced osmolarity oral rehydration solution for treating dehydration due to diarrhoea in children: systematic review.

Autor: Fuchs, Hahn, Seokyung, Kim, YaeJean, Garner, Paul
Předmět:
Zdroj: BMJ: British Medical Journal (International Edition); 7/14/2001, Vol. 323 Issue 7304, p81, 5p, 4 Charts, 1 Graph
Abstrakt: Results: In a meta-analysis of nine trials for the primary outcome, reduced osmolarity rehydration solution was associated with fewer unscheduled intravenous infusions compared with standard WHO rehydration solution (odds ratio 0.61, 95% confidence interval 0.47 to 0.81). Three trials reported that no patients required unscheduled intravenous infusion. Trials reporting secondary outcomes suggested that in the reduced osmolarity rehydration solution group, stool output was lower (standardised mean difference in the log scale 0.214 (95% confidence interval 0.305 to 0.123; 13 trials) and vomiting was less frequent (odds ratio 0.71, 0.55[ ]to 0.92; six trials). Six trials sought presence of hyponatraemia, with events in three studies, but no significant difference between the two arms. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index