| Autor: |
Andreas J. Steiner, Arnold E. Stütz, Chris A. Tarling, Stephen G. Withers, Tanja M. Wrodnigg |
| Zdroj: |
Australian Journal of Chemistry; Jun2009, Vol. 62 Issue 6, p553-557, 5p |
| Abstrakt: |
1,5-Dideoxy-1,5-iminoxylitol–amino acid hybrids have been synthesized by cyclisation via a double reductive amination of xylo-pentodialdose and the respective amino groups of lysine as well as serine components. Further modification with aromatic substituents gave access to lipophilic derivatives. Kinetic studies revealed that all compounds exhibited better inhibitory properties against β-xylosidase from Thermoanaerobacterium sacharolyticumthan the parent iminosugar. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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