| Autor: |
Kitajima, Tsuyoshi, Kanbayashi, Takashi, Saitoh, Yasushi, Ogawa, Yuriko, Sugiyama, Tomonari, Kaneko, Yoshihiko, Sasaki, Yoshiko, Aizawa, Rika, Shimisu, Tetsuo |
| Předmět: |
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| Zdroj: |
Psychiatry & Clinical Neurosciences; Jun2001, Vol. 55 Issue 3, p299-300, 2p |
| Abstrakt: |
Abstract We investigated the influence of melatonin on the human autonomic functions by measuring muscle sympathetic nerve activity (MSNA). Five healthy male volunteers took 3 mg of melatonin, and their plasma melatonin concentration, blood pressure, heart rate, and burst rate of MSNA were then recorded. The peak level of melatonin concentration showed a marked interindividual variation. Blood pressure was reduced significantly, while heart rate and burst rate of MSNA did not change significantly. These results indicate that melatonin has a hypotensive effect on blood pressure, and the central cardiovascular regulatory mechanism such as lowering of the baroreflex setpoint would be involved in the effect. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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