| Autor: |
Sabeta, Claude, Blumberg, Lucille, Miyen, Jacobeth, Mohale, Debra, Shumba, Wonderful, Wandeler, Alex |
| Předmět: |
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| Zdroj: |
FEMS Immunology & Medical Microbiology; Feb2010, Vol. 58 Issue 1, p85-90, 6p, 1 Diagram, 2 Charts, 1 Map |
| Abstrakt: |
Isolations of Mokola virus (MOKV) are rare, but in South Africa and Zimbabwe this genotype 3 lyssavirus variant has been occasionally found in domestic mammals (cats and a dog) with a total of 17 virus isolates (South Africa 10, Zimbabwe 7) having been recovered during the past 30 years. We report the identification of a MOKV isolate involved in a human contact in Grahamstown (Eastern Cape, South Africa) and a genetic comparison with previously characterized isolates. This reported MOKV case was in a previously immunized cat. While the continual recovery of MOKV isolates in domestic cats is speculative of the existence of a reservoir host species among bats or rodents, the lack of protection with currently used vaccines is discussed and the need for biologicals with a wider spectrum of protection against this lyssavirus variant is highlighted. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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