Induction of TNF-alpha and MnSOD by endotoxin: role of membrane CD14 and Toll-like receptor-4.

Autor: Min-Fu Tsan, Clark, Robert N., Goyert, Sanna M., White, Jullie E.
Předmět:
Zdroj: American Journal of Physiology: Cell Physiology; Jun2001, Vol. 280 Issue 6, pC1422, 9p, 18 Diagrams, 13 Graphs
Abstrakt: Studies the role of membrane CD14 and Toll-like receptor-4 in the induction of tumor necrosis factor (TNF)-alpha and manganese superoxide dismutase (MnSOD) by endotoxin. Role of mCD14 in lipolysaccharide (LPS) induction of TNF-alpha and MnSOD; Effect of Tlr4 gene point mutation on LPS induction of TNF-alpha.
Databáze: Complementary Index