| Abstrakt: |
ALCHORNEA FLORIBUNDA (Euphorbiaceae) leaves are widely used in African ethnomedicine for the management of acute and chronic inflammatory disorders. In the present study, bioactivity-guided fractionation led to the isolation of two known ( 1 and 3) and one new ( 2) stigmastane steroids from the hexane extract of ALCHORNEA FLORIBUNDA leaves. The anti-inflammatory activities of these compounds were evaluated using IN VITRO and IN VIVO animal models. The compounds 1, 2, and 3 at 50 and 100??g/ear significantly (p?
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