| Autor: |
Chu, Y., Hu, H.-M., Winter, H., Wood, W. J., Doran, T., Lashley, D., Bashey, J., Schuster, J., Wood, J., Lowe, B. A., Vetto, J. T., Weinberg, A. D., Puri, R., Smith II, J. W., Urba, W. J., Fox, B. A. |
| Předmět: |
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| Zdroj: |
European Journal of Nuclear Medicine; Mar2006 Supplement 1, Vol. 26, pS50, 4p |
| Abstrakt: |
Abstract. Recently, it was recognized that an immune response develops along one of two major pathways. One leads to a destructive immune response (type 1), while the alternative leads to a nondestructive immune response (type 2). Our studies in animal models suggest that therapeutic vaccines induce a tumor-specific type 1 immune response while ineffective vaccines induce a type 2 response. These results have led us to examine the immune response in sentinel lymph nodes draining tumor vaccines of patients entered onto clinical trials for melanoma, breast and renal cell cancer. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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