| Autor: |
Schirrmeister, Holger, Kühn, Thorsten, Guhlmann, Albrecht, Santjohanser, Claudia, Hörster, Thomas, Nüssle, Karin, Koretz, Karin, Glatting, Gerhard, Rieber, Andrea, Kreienberg, Rolf, Buck, Andreas C, Reske, Sven N |
| Předmět: |
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| Zdroj: |
European Journal of Nuclear Medicine; 2001, Vol. 28 Issue 3, p351, 8p |
| Abstrakt: |
Abstract. The present study compared the diagnostic accuracy of fluorine-18 2-deoxy-2-fluoro-D-glucose positron emission tomography (FDG-PET) with conventional staging techniques. The differentiation between malignant and benign lesions and the detection of multifocal disease, axillary and internal lymph node involvement, and distant metastases were evaluated. One hundred and seventeen female patients were prospectively examined using FDG-PET and conventional staging methods such as chest X-ray, ultrasonography of the breast and liver, mammography and bone scintigraphy. All patients were examined on a modern full-ring PET scanner. Histopathological analysis of resected specimens was employed as the reference method. The readers of FDG-PET were blinded to the results of the other imaging methods and to the site of the breast tumour. The sensitivity and specificity of FDG-PET in detecting malignant breast lesions were 93% and 75% respectively. FDG-PET was twofold more sensitive (sensitivity 63%, specificity 95%) in detecting multifocal lesions than the combination of mammography and ultrasonography (sensitivity 32%, specificity 93%). Sensitivity and specificity of FDG-PET in detecting axillary lymph node metastases were 79%... [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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