Factors influencing lopinavir and atazanavir plasma concentration.

Autor: Stöhr, Wolfgang, Back, David, Dunn, David, Sabin, Caroline, Winston, Alan, Gilson, Richard, Pillay, Deenan, Hill, Teresa, Ainsworth, Jonathan, Gazzard, Brian, Leen, Clifford, Bansi, Loveleen, Fisher, Martin, Orkin, Chloe, Anderson, Jane, Johnson, Margaret, Easterbrook, Philippa, Gibbons, Sara, Khoo, Saye
Předmět:
Zdroj: Journal of Antimicrobial Chemotherapy (JAC); Jan2010, Vol. 65 Issue 1, p129-137, 9p, 3 Charts, 1 Graph
Abstrakt: Background: The protease inhibitors lopinavir and atazanavir are both recommended for treatment of HIV-infected patients. Considerable inter-individual variability in plasma concentration has been observed for both drugs. The aim of this study was to evaluate which demographic factors and concomitant drugs are associated with lopinavir and atazanavir plasma concentration. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index