Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and β-catenin expression.

Autor: Nagy, Irina I., Railo, Antti, Rapila, Risto, Hast, Terhi, Sormunen, Raija, Tavi, Pasi, Räsänen, Juha, Vainio, Seppo J.
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Zdroj: Cardiovascular Research; Jan2010, Vol. 85 Issue 1, p100-109, 10p, 5 Diagrams, 1 Chart, 1 Graph
Abstrakt: Aims: The stage-dependent organization of the cardiomyocytes during formation of the different layers of the developing ventricular wall is critical for the establishment of a functional heart, but the instructive signals involved are still poorly known. We have addressed the potential role of Wnt-11 in the control of early ventricular myocardium assembly. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index