| Autor: |
Jie Peng, Yang-Kai Wang, Li-Gang Wang, Wen-Jun Yuan, Ding-Feng Su, Xin Ni, Xiao-Ming Deng, Wei-Zhong Wang |
| Předmět: |
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| Zdroj: |
Cardiovascular Research; Nov2009, Vol. 84 Issue 2, p283-291, 9p, 1 Chart, 5 Graphs |
| Abstrakt: |
Aims: The central antihypertensive drug moxonidine lowers blood pressure (BP) through stimulating an imidazoline receptor within the rostral ventrolateral medulla (RVLM). Nitric oxide (NO) generated by the inducible NO synthase (iNOS) in the RVLM has been suggested to be involved in tonic sympathetic inhibition. The aim of this study was to determine the role of NO generated by iNOS in mediating moxonidine-induced cardiovascular inhibition in rats. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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