| Autor: |
Beretta-Piccoli, Benedetta C., Sauvain, Marie J., Gal, Imre, Schibler, Andreas, Saurenmann, Traudel, Kressebuch, Helene, Bianchetti, Mario G., Beretta-Piccoli, B C, Sauvain, M J, Gal, I, Schibler, A, Saurenmann, T, Kressebuch, H, Bianchetti, M G |
| Předmět: |
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| Zdroj: |
European Journal of Pediatrics; 2000, Vol. 159 Issue 8, p594-601, 8p |
| Abstrakt: |
Unlabelled: Chronic recurrent multifocal osteomyelitis is a rare chronic inflammatory musculoskeletal process observed in children and young adults. Recently, the acronym SAPHO syndrome (for synovitis, acne, pustulosis, hyperostosis, osteitis) was coined to emphasise the association between osteo-articular inflammations and different skin abnormalities which are aseptic and filled with neutrophils. In adults, chronic recurrent multifocal osteomyelitis is now a classical manifestation of SAPHO syndrome. Chronic skin disorders were seen in eight of ten children on follow-up at the University Children's Hospitals in Bern and Zurich and in 61 of 260 paediatric cases reported in the literature. The different skin lesions were palmoplantar pustulosis (n = 40), non-palmoplantar pustulosis (n = 6), psoriasis vulgaris (n = 16) or severe acne (n = 4). More rarely Sweet syndrome (n = 2) or pyoderma gangrenosum (n = 1) were reported.Conclusion: The synovitis, acne, pustulosis, hyperostosis, osteitis syndrome is pertinent even in paediatrics since skin involvement is frequent. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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