Outcome predictors in nitric oxide treated preterm infants.

Autor:	Dimitriou, G., Greenough, A., Kavvadia, V., Devane, S. P., Rennie, J. M.
Předmět:	PREMATURE infant death THERAPEUTIC use of nitric oxide CHI-squared test CLINICAL trials COMPARATIVE studies LONGITUDINAL method RESEARCH methodology MEDICAL cooperation NITRIC oxide NONPARAMETRIC statistics RESEARCH RESPIRATORY distress syndrome SURVIVAL analysis (Biometry) SURVIVAL EVALUATION research TREATMENT effectiveness PREDICTIVE tests OXYGEN consumption INHALATION administration
Zdroj:	European Journal of Pediatrics; 1999, Vol. 158 Issue 7, p589-591, 3p
Abstrakt:	Unlabelled: Our aim was to identify factors predictive of death in preterm infants in whom inhaled nitric oxide was administered in response to poor oxygenation (oxygenation index > or =15). Of the 23 (median gestational age 28 weeks, range 24-36) infants consecutively so treated, 15 died. Non-survival was commoner in infants with air leaks (12 of 12, P < 0.002) and/or a change in their oxygenation index of less than 30% in response to inhaled nitric oxide administration (P < 0.05).Conclusion: In preterm infants given inhaled nitric oxide because of poor oxygenation, a diagnosis of airleak and a lack of initial response are predictive of death. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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