Plasmid-mediated TEM-3 extended-spectrum beta-lactamase production in Salmonella typhimurium in Casablanca.

Autor: AitMhand, Rajaa, Soukri, Abdelaziz, Moustaoui, Najat, Amarouch, Hamid, ElMdaghri, Naima, Sirot, Danielle, Benbachir, Mohamed
Zdroj: Journal of Antimicrobial Chemotherapy (JAC); Jan2002, Vol. 49 Issue 1, p169-172, 4p
Abstrakt: Isolates of extended-spectrum beta-lactamase (ESBL)-producing Salmonella typhimurium were recovered from children admitted to the IbnRochd University Hospital of Casablanca in 1994. These isolates produced TEM-3 as shown by PCR, isoelectric focusing and sequencing. Production of TEM-3 and resistance to gentamicin were encoded by a 10 kb plasmid that could be transferred by conjugation and transformation. This report extends the list of ESBLs produced by S. typhimurium and stresses the need for continuous surveillance of non-typhoidal Salmonella to adapt antibiotic treatment and preventive measures. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index