| Autor: |
Tao, Jun, Tamis, Robert, Fink, Katharine, Williams, Brenda, Nelson-White, Tresa, Craig, Randall |
| Předmět: |
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| Zdroj: |
Human Reproduction; Jun2002, Vol. 17 Issue 6, p1513-1518, 6p |
| Abstrakt: |
Background: This retrospective study analysed the outcomes of 339 embryo transfers on either day 3 (n = 97) or day 4 (n = 242), and proposed a grading system for morula/compact embryos.Methods: The morula/compact embryo grading was based on: (i) the proportion of blastomeres undergoing the compaction process; (ii) the morphology of the compacted multicellular mass; (iii) the embryo quality on day 2 and 3; and (iv) the amount of fragmentation. Embryo transfers were classified into groups as follows: group I: transferred with zero 'good' embryos; group II: one 'good' embryo; group III: two or more 'good' embryos.Results: Patients on day 4 were transferred with significantly fewer embryos in groups II and III (2.58 +/- 0.9 and 2.35 +/- 0.6 respectively) when compared with the correspondent day 3 transfers (3.81 +/- 1.4 and 4.07 +/- 0.9 respectively) (P < 0.05), but had the same or higher implantation and pregnancy rates. Analysing the patients who had transfers with all 'good' embryos, day 4 transfer achieved a significantly higher implantation rate compared with day 3 transfer (46.4 versus 21.4%, P < 0.01), but the number of embryos transferred on day 4 was significantly lower than day 3 (2.1 +/- 0.5 versus 3.5 +/- 0.9, P < 0.01).Conclusions: The morula/compact embryos had great value for embryo selection, which significantly reduced the number of embryos needed for transfer. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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