Analysis of Individual Specific Cytotoxic T Lymphocytes for Two MAGE-3-derived Epitopes Presented by HLA-A24.

Autor: Katsura, Fumihiro, Eura, Masao, Chikamatsu, Kazuaki, Oiso, Masatake, Yumoto, Eiji, Ishikawa, Takeru
Zdroj: Japanese Journal of Clinical Oncology; Mar2000, Vol. 30 Issue 3, p117, 5p
Abstrakt: Describes the generation of specific cytotoxic T lymphocyte (CTL) lines of peptides that are immunodominant in generating MAGE-3-specific and human leukocyte antigen (HLA)-A24-restricted CTL. Induction of CTL that are specific for MAGE-3-derived peptides in HLA-A24[sup +] individuals; Recognition of cancer cell lines expressing both HLA-A24 molecules and MAGE-3 gene by the peptide-specific CTL.
Databáze: Complementary Index