Evaluation of a single-step diagnosis and treatment of premalignant cervical lesion by LEEP

Autor:	Emam, Mohamed, Elnashar, Aboubakr, Shalan, Hesham, Barakat, Rafik
Předmět:	CERVICAL cancer diagnosis ELECTROSURGERY ONCOLOGIC surgery SURGICAL excision ACETIC acid COLPOSCOPY CANCER histopathology THERAPEUTICS BIOPSY COMPARATIVE studies DEVELOPING countries RESEARCH methodology MEDICAL cooperation RESEARCH CERVIX uteri tumors EVALUATION research CERVICAL intraepithelial neoplasia DIAGNOSIS
Zdroj:	International Journal of Gynecology & Obstetrics; Dec2009, Vol. 107 Issue 3, p224-227, 4p
Abstrakt:	Objective: To explore whether a single-step diagnosis and treatment of premalignant cervical lesions by the loop electrosurgical excision procedure (LEEP) is appropriate in women at high risk in low-resource countries.Method: Sixty women suspected of having a high-grade lesion on both visual inspection with acetic acid (VIA) and colposcopic examination were randomly allotted to one of 2 groups. In group 1, LEEP was performed immediately and a tissue specimen was sent for histopathologic evaluation; in group 2, a punch biopsy was performed, followed by a histopathologic evaluation; then, LEEP was performed if needed.Results: Among the patients who underwent LEEP, 4 (16%) in group 1 and 3 (15.8%) in group 2 were overtreated. No patients dropped out of the study in group 1 but 5 (20.8%) did in group 2.Conclusion: The single-step diagnosis and LEEP treatment of premalignant cervical lesions is appropriate in low-resource countries. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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