| Autor: |
Tokuhiro, Yumiko, Yoshida, Tomoko, Nakabayashi, Yoshinobu, Nakauchi, Shohei, Nakagawa, Yumi, Kihara, Minako, Mitsufuji, Nobuto, Kizaki, Zenro |
| Předmět: |
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| Zdroj: |
Pediatrics International; Dec2009, Vol. 51 Issue 6, p804-806, 3p, 2 Charts |
| Abstrakt: |
Background: The relationship between oxygen and retinopathy of prematurity (ROP) has been studied frequently, and a pulse oximeter has the potential to facilitate the control of oxygen fluctuation in neonates. The objective of the present study was to compare the incidence of threshold ROP (stage 3 requiring laser treatment and stage 4) in infants of <33 weeks gestation after implementing a new clinical O2 management practice. Methods: A retrospective study of data from the Kyoto First Red Cross Hospital neonatal intensive care unit (NICU) from 1 July 2004 to 31 October 2007 (closed 1 December 2006–30 March 2007 for reconstruction). A reduced oxygen protocol was implemented to maintain oxygen saturation (SpO2) values using a pulse oximeter between 88% and 92%. The incidence of threshold ROP in the earlier period (1 July 2004–31 December 2005) and the later period (1 January 2006–31 October 2007) were compared. Results: The incidence of threshold ROP significantly decreased from 32.2% to 16.7%, after changing to the reduced oxygen protocol ( P < 0.05). Conclusion: A significant decrease in the rate of threshold ROP in infants of <33 weeks gestation was observed after implementation of the new clinical O2 management practice. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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