Recombinant human acid α-glucosidase: high level production in mouse milk, biochemical characteristics, correction of enzyme deficiency in GSDII KO mice.

Autor: Bijvoet, Agnes G. A., Kroos, Marian A., Pieper, Frank R., Van der Vliet, Martin, De Boer, Herman A., Van der Ploeg, Ans T., Verbeet, Martin Ph., Reuser, Arnold J. J.
Zdroj: Human Molecular Genetics; Nov98, Vol. 7 Issue 11, p1815, 10p, 6 Black and White Photographs, 11 Diagrams, 4 Charts, 1 Graph
Abstrakt: Studies recombinant human acid alpha glucosidase. Biochemical characteristics of alpha glucosidase; Enzyme replacement therapy for alpha glucosidase deficiency; Therapeutic potential of the recombinant enzyme.
Databáze: Complementary Index