Shear stress-induced vasodilation in porcine coronary conduit arteries is independent of nitric oxide release.

Autor: Dube, Sandeep, Canty Jr., John M.
Předmět:
Zdroj: American Journal of Physiology: Heart & Circulatory Physiology; Jun2001, Vol. 280 Issue 6, pH2581, 10p, 2 Charts, 5 Graphs
Abstrakt: Features a study which determined the importance of nitric oxide in eliciting epicardial coronary artery dilation during sustained increases in shear stress in the absence of pulsatile flow. Experiments demonstrating efficacy of nitric oxide (NO) synthase inhibition; Efficacy of nitro-L-arginine methyl ester in inhibiting NO synthase; Relation between shear stress level and diameter in coronary conduit arteries; Mechanisms of vasodilation to steady flow.
Databáze: Complementary Index