Synthesis from L-menthol of optically active macrolides with N-containing (azine or hydrazide) groups.

Autor: Ishmuratov, G. Yu., Mingaleeva, G. R., Yakovleva, M. P., Muslukhov, R. R., Vyrypaev, E. M., Galkin, E. G., Tolstikov, A. G.
Předmět:
Zdroj: Chemistry of Natural Compounds; Jul2009, Vol. 45 Issue 4, p470-473, 4p
Abstrakt: Potentially useful 15- and 20-membered macrolides containing azine or hydrazide groups were synthesized from L-menthol via [1+1]-condensation at room temperature of 3 R,7-dimethyl-6-oxooctyl-3 R,7-dimethyl-6-oxooctanoate, which was obtained from 3 R,7-dimethyl-6-oxooctanal via a Tishchenko reaction, with hydrazine hydrate or malonic acid dihydrazide. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index