| Autor: |
Doodes, Paul D., Yanxia Cao, Hamel, Keith M., Yumei Wang, Rodeghero, Rachel L., Kobezda, Tamas, Finnegan, Alison |
| Předmět: |
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| Zdroj: |
Arthritis & Rheumatism; Oct2009, Vol. 60 Issue 10, p2945-2953, 9p |
| Abstrakt: |
The article presents a study on the role of chemokine (C-C motif) receptor 5 (CCR5) and its ligands in inflammatory cell enlisting into the joint. The study induces arthritis to wild-type and CCR5-deficient mice by immunizing with human proteoglycan (PG) in adjuvant, and measures the chemokines and cytokines expressions through enzyme-linked immunosorbent. Result shows that the increase in arthritis intensity in CCR5-deficient mice linked with high level of chemokine (C-C motif) ligand 5 (CCL5). |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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