Randomized trial of conversion from mycophenolate mofetil to azathioprine 6 months after renal allograft transplantation.

Autor: Wüthrich, Rudolf P., Cicvara, Snjezana, Ambühl, Patrice M., Binswanger, Ulrich
Zdroj: Nephrology Dialysis Transplantation; Aug2000, Vol. 15 Issue 8, p1228-1231, 4p
Abstrakt: Background. In the first year after renal allograft transplantation, triple therapy immunosuppression with cyclosporin (CsA), prednisone (P), and mycophenolate mofetil (MMF) is superior to a triple therapy treatment that includes azathioprine (AZA) instead of MMF. Whether long‐term treatment with CsA‐P‐MMF is better than treatment with CsA‐P‐AZA is a matter of debate, as 3‐year graft survival is similar in MMF‐ and AZA‐treated patients. The purpose of the present study was to examine the short‐term effect of changing MMF to AZA in low‐risk renal allograft recipients 6 months after transplantation. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index