Renal and haemodynamic effects of amlodipine and nifedipine in hypertensive renal transplant recipients.

Autor: Venkat-Raman, G, Feehally, J, Elliott, HL, Griffin, P, Moore, RJ, Olubodun, JOB, Wilkinson, R
Zdroj: Nephrology Dialysis Transplantation; Oct1998, Vol. 13 Issue 10, p2612-2616, 5p
Abstrakt: Background.Immunosuppressive treatment with cyclosporin A (CsA) improves the survival of renal allografts, but is associated with renal vasoconstriction and hypertension. Previous reports suggest that the calcium-channel blockers nifedipine and amlodipine may improve graft function in CsA-treated patients. We have compared the effects of amlodipine (5-10 mg once daily) and nifedipine retard (10-40 mg twice daily) on renal function and blood pressure in renal transplant recipients treated with CsA. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index